Clobetasol Propionate
Commercial
Anti-inflammatory
IP/ BP / USP/ EP
21522 –46– 7
CEP No. R1-CEP 2009 – 315-Rev 02
ANVISA, KFDA, CDE-NMPA
Application - cream, foam, gel, lotion, ointment, shampoo, solution, emollient
Drug Description
Clobetasol propionate is indicated to treat moderate to severe plaque psoriasis. Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. Corticosteroids have a wide therapeutic window as patients may require doses that are multiples of what the body naturally produces. Patients taking corticosteroids should be counselled regarding the risk of hypothalamic-pituitary-adrenal axis suppression and increased susceptibility to infections.

